R packages by markusboenn

POD - Probability of Detection for Qualitative PCR Methods

This tool computes the probability of detection (POD) curve and the limit of detection (LOD), i.e. the number of copies of the target DNA sequence required to ensure a 95 % probability of detection (LOD95). Other quantiles of the LOD can be specified. This is a reimplementation of the mathematical-statistical modelling of the validation of qualitative polymerase chain reaction (PCR) methods within a single laboratory as provided by the commercial tool 'PROLab' <http://quodata.de/>. The modelling itself has been described by Uhlig et al. (2015) <doi:10.1007/s00769-015-1112-9>.

Last updated 5 years ago

4.70 score 10 scripts 140 downloads

fitteR - Fit Hundreds of Theoretical Distributions to Empirical Data

Systematic fit of hundreds of theoretical univariate distributions to empirical data via maximum likelihood estimation. Fits are reported and summarized by a data.frame, a csv file or a 'shiny' app (here with additional features like visual representation of fits). All output formats provide assessment of goodness-of-fit by the following methods: Kolmogorov-Smirnov test, Shapiro-Wilks test, Anderson-Darling test.

Last updated 3 years ago

1.00 score 6 scripts 203 downloads